Cosmetic Raw Materials Poloxamer 184 188 407 White Powder CAS 9003-11-6 CAS NO.9003-11-6

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Cosmetic Raw Materials Poloxamer 184 188 Poloxamer 407 CAS 9003-11-6

Description:
Poloxamer is a block copolymer consisting of polyethylene glycol (PEG) and polypropylene glycol (PPG) units. It is available in various grades with different molecular weights and ratios of PEG to PPG segments. The most commonly used grades include Poloxamer 188 (also known as Pluronic F68) and Poloxamer 407 (Pluronic F127).

Specification:

• Chemical Formula: Variable, depending on the specific grade
• Appearance: Clear or slightly turbid liquid, or white waxy solid
• Molecular Weight: Varies depending on the specific grade
• Solubility: Soluble in water and many organic solvents

Application:
Poloxamer finds a wide range of applications, including:

1. Pharmaceutical Industry: Poloxamer is extensively used in pharmaceutical formulations. It acts as a solubilizer, emulsifier, and stabilizer in various oral, topical, and parenteral dosage forms. It can improve the solubility of poorly soluble drugs, enhance drug delivery, and modify the rheological properties of formulations. It is commonly found in ophthalmic solutions, creams, gels, and suppositories.

2. Cosmetics and Personal Care Products: Poloxamer is used in cosmetics and personal care products as an emulsifier, dispersant, and stabilizer. It helps to create stable emulsions, improve product texture, and enhance the spreadability of formulations. It is found in creams, lotions, shampoos, and other skincare and haircare products.

3. Industrial Applications: Poloxamer is utilized in various industrial processes. It is used as a lubricant, antistatic agent, and emulsifier in the textile, paper, and plastics industries. It can also be used in cleaning products, metalworking fluids, and as a dispersant in paints and coatings.

Features:

• Nonionic Surfactant: Poloxamer is a nonionic surfactant, meaning it does not carry an electric charge in solution. This property makes it compatible with a wide range of other ingredients and formulations.

• Thermoresponsive Behavior: Some Poloxamer grades, such as Poloxamer 407, exhibit a thermoresponsive behavior. They can undergo a sol-gel transition at higher concentrations, forming a gel at lower temperatures. This property is advantageous in the formulation of certain drug delivery systems and topical gels.

• Biocompatibility: Poloxamer is generally considered biocompatible and non-toxic. It has low irritancy and is well-tolerated by the skin and mucous membranes. However, specific grades and concentrations should be evaluated for safety in each application.

• Solubility: Poloxamer is highly soluble in water and can form clear solutions over a wide range of concentrations. It can also be soluble in various organic solvents, allowing for versatility in formulation.

 

Product Name	Cosmetic Raw Materials CAS 9003-11-6 poloxamer 184 188 Poloxamer 407
Appearance	white powder
Grade	Cosmetic Grade
Specification	99%
Keywords	poloxamer 184；poloxamer 188；Poloxamer 407
Storage	Keep in a cool, dry, dark location in a tightly sealed container or cylinder.
Shelf Life	24 Months

 

 

What is poloxamer

 

Poloxam is a novel polymer emulsifier, known as Poloxam 184 by BASF Pluracare® L 64. It has excellent cleaning and emulsifying properties, is gentle on the skin, and is widely used in makeup remover products. In addition, poloxam 184 has excellent solubility and is used as a solvent in cosmetics.

Function of poloxamer

 

Poloxam 184 is used as detergent, surfactant and suspending agent in cosmetics. It has a certain irritation.

Packaging	1kg-15kg packing	2 PE bag inside + 1 foil bag outside in carton
	25kg-50kg packing	2 PE bag inside + 1 foil bag outside in drum
	Other packing	Customized packing
Drum Size	D38cm*H60cm or customized, 25 kg/ drum
Shipping	1-50kg	International Express	Fast and convenient	Door to Door
	50-500kg	Air Transportation	Fast and cheap	To Air Port
	Above 500kg	Sea Transportation	Cheap and convenient	To Port

 

 

 

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