99% Pure White to off-white CAS 83-49-8 Hyodeoxycholic Acid/Hdca Powder CAS NO.83-49-8

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99% Pure White to off-white CAS 83-49-8 Hyodeoxycholic Acid/Hdca Powder

 

Description:
Hyodeoxycholic acid is a steroidal compound and one of the primary bile acids found in the bile of pigs (hence the prefix "hypo-," indicating pig origin). It is structurally similar to other bile acids, such as cholic acid and deoxycholic acid, but with minor differences in the arrangement of hydroxyl groups.

Specification:

• Chemical formula: C24H40O4
• CAS Number: 83-49-8
• Molecular weight: 392.57 g/mol
• Appearance: White or off-white crystalline powder
• Solubility: Hyodeoxycholic acid is practically insoluble in water but soluble in organic solvents like ethanol and chloroform.

Application:

1. Pharmaceutical Industry: Hyodeoxycholic acid has been used in the pharmaceutical industry for various purposes. It is an intermediate in the synthesis of ursodeoxycholic acid (UDCA), which is used medically for the treatment of gallstones, liver disorders, and certain gastrointestinal conditions. HDCA is converted to UDCA through a chemical modification process.

2. Research and Development: Hyodeoxycholic acid is used in research and development studies related to bile acids and their physiological functions. It helps in understanding the role of bile acids in digestion, fat absorption, cholesterol metabolism, and other biological processes.

Features:

1. Bile Acid Function: Hyodeoxycholic acid, like other bile acids, plays a crucial role in the digestion and absorption of dietary fats. It aids in the emulsification and solubilization of fats, facilitating their breakdown by digestive enzymes and subsequent absorption in the intestines.

2. Choleretic Properties: Hyodeoxycholic acid has choleretic properties, meaning it promotes the secretion of bile from the liver and its release into the digestive tract. Bile plays a vital role in the digestion and absorption of fats, as well as the elimination of waste products from the body.

3. Synthesis of Ursodeoxycholic Acid: Hyodeoxycholic acid serves as an intermediate compound in the synthesis of ursodeoxycholic acid (UDCA). UDCA has therapeutic applications in various liver and gallbladder disorders and is derived from HDCA through a chemical modification process.

4. Bioavailability: Hyodeoxycholic acid is poorly absorbed in the intestines and is primarily excreted in the feces. Its limited bioavailability contributes to its function as a bile acid in the digestive process.

5. Regulation of Cholesterol: Bile acids, including hyodeoxycholic acid, are involved in the regulation of cholesterol metabolism. They help in the elimination of excess cholesterol from the body by forming mixed micelles with cholesterol and facilitating its excretion.

 

Products Description

 

Product Name	Hdca/Hyodesoxycholic Acid
CAS	83-49-8
Appearance	White to off-white powder
Molecular formula	C24H40O4
Assay	99%
Shelf Life	24 months when properly stored
Storage	Keep in a cool, dry, dark location

 

Application&Function

It is suitable for Ia and Ib hyperlipidemia and atherosclerosis. It has a certain bacteriostatic effect against pertussis, diphtheria,Staphylococcus
aureus, etc. It is also suitable for choledocholithiasis, cholecystitis, cholelithiasis, and other non-obstructive cholestasis. It accelerates the
discharge of gallbladder contrast media from the liver to facilitate imaging. Can promote intestinal fat decomposition and fat-soluble vitamin
absorption, can be used for liver and gallbladder diseases caused by indigestion. It can be used as anti-inflammatory drugs to treat chronic
bronchitis and viral respiratory tract inflammation in children. I can cause gastrointestinal discomfort, mild diarrhea and so on.

 

 

Specification

TESTS	SPECIFICATIONS&LIMITS	RESULTS
Characters	White or white crystalline powder	Complies
Solubility	slightly soluble in water, freely soluble in	Complies
	alcohol and in chl oroform
Identification	IR: Corresponding to Praziquantel CRS	Positive
Melting Range	136°C~142°C	137.8~139.5°C
Heavy metals	Not more than 0.002%	<0.002%
Phosphate	Not more than 0.05%	<0.05%
Loss on drying	Not more than 0.5%	0.24%
Residue on ignition	Not more than 0.1%	0.03%
	Related compound A: not more than 0.2%	A: 0.09%
Related Substances	Related compound B: not more than 0.2%	B: 0.11%
	Related compound C: not more than 0.2%	C:Not detectable
Assay	98.5%~101.0% (dried basis)	99.38%
Particle size		20% less than 10um
		97% less than 50um
Residual Solvents	Limit of chloroform: NMT 60 ppm	NMT 60 ppm
	Limit: NMT 500 ppm	NMT 500 ppm
Conclusion	Conform with USP32

Packaging	1kg-15kg packing	2 PE bag inside + 1 foil bag outside in carton
	25kg-50kg packing	2 PE bag inside + 1 foil bag outside in drum
	Other packing	Customized packing
Drum Size	D38cm*H60cm or customized, 25 kg/ drum
Shipping	1-50kg	International Express	Fast and convenient	Door to Door
	50-500kg	Air Transportation	Fast and cheap	To Air Port
	Above 500kg	Sea Transportation	Cheap and convenient	To Port

 

 

 

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