99% Purity CAS 55268-74-1 Praziquantel for Anti-worm Medication CAS NO.55268-74-1

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99% Purity CAS 55268-74-1 Praziquantel Powder for Anti-worm Medication

 

Description:
Praziquantel is a synthetic compound with anthelmintic properties. It belongs to the class of isoquinoline derivatives. It is available in the form of tablets or oral suspension for administration.

Specification:

• Chemical formula: C19H24N2O2
• CAS Number: 55268-74-1
• Molecular weight: 312.41 g/mol
• Appearance: White to off-white crystalline powder
• Solubility: Praziquantel is practically insoluble in water but soluble in organic solvents like ethanol and chloroform.

Application:

1. Human Medicine: Praziquantel is primarily used in human medicine for the treatment of parasitic infections, particularly those caused by flatworms, such as Schistosoma spp. (causing schistosomiasis) and various species of tapeworms. It is considered the drug of choice for these infections.

2. Veterinary Medicine: Praziquantel is widely used in veterinary medicine to treat parasitic infections in animals, including dogs, cats, livestock, and fish. It is effective against tapeworms, flukes, and other internal parasites commonly found in animals.

Features:

1. Broad-Spectrum Activity: Praziquantel exhibits a broad-spectrum activity against a wide range of parasites. It is highly effective against various species of flatworms (trematodes and cestodes) that infect humans and animals.

2. Mechanism of Action: Praziquantel works by disrupting the integrity of the parasites' cell membranes, leading to muscle paralysis and subsequent death of the parasites. It is believed to affect the calcium ion channels in the parasites' cells.

3. High Efficacy: Praziquantel is known for its high efficacy in treating parasitic infections. It has a rapid onset of action and is effective against both adult and larval stages of the parasites.

4. Safety: Praziquantel is generally considered safe and well-tolerated when used at recommended doses. Side effects, if any, are usually mild and transient, including gastrointestinal disturbances such as abdominal pain, nausea, and diarrhea.

5. Administration: Praziquantel is typically administered orally, either in tablet or suspension form. The dosage and duration of treatment depend on the specific parasite being targeted and the patient's age and weight.

6. Resistance: Although rare, there have been isolated reports of resistance to praziquantel in certain parasite species. However, it remains highly effective against the majority of parasitic infections, and resistance is not commonly encountered.

 

Products Description

Product Name	Praziquantel
CAS No	55268-74-1
Appearance	White Powder
Purity	99%

Praziquantel (Biltricide) is an anthelmintic effective against flatworms. Praziquantel is on the World Health Organization's List of Essential Medicines,a list of the most important medications needed in a basic health system. Praziquantel is not licensed for use in humans in the UK;it is,however,available as a veterinary anthelmintic,and is available for use in humans on a named-patient basis.

 

Application&Function

(1) Praziquantel has a particularly dramatic effect on patients with schistosomiasis. Studies of those treated have shown that within six months of receiving a dose of praziquantel.
(2) Praziquantel is an anthelmintic or anti-worm medication. It prevents newly hatched insect larvae (worms) from growing or multiplying in your body.
(3) Praziquantel is also used to treat infection with liver flukes, caused by a type of worm found in East Asia. This worm enters the body while eating contaminated fish.

Specification

TESTS	SPECIFICATIONS&LIMITS	RESULTS
Characters	White or white crystalline powder	Complies
Solubility	slightly soluble in water, freely soluble in	Complies
	alcohol and in chl oroform
Identification	IR: Corresponding to Praziquantel CRS	Positive
Melting Range	136°C~142°C	137.8~139.5°C
Heavy metals	Not more than 0.002%	<0.002%
Phosphate	Not more than 0.05%	<0.05%
Loss on drying	Not more than 0.5%	0.24%
Residue on ignition	Not more than 0.1%	0.03%
	Related compound A: not more than 0.2%	A: 0.09%
Related Substances	Related compound B: not more than 0.2%	B: 0.11%
	Related compound C: not more than 0.2%	C:Not detectable
Assay	98.5%~101.0% (dried basis)	99.38%
Particle size		20% less than 10um
		97% less than 50um
Residual Solvents	Limit of chloroform: NMT 60 ppm	NMT 60 ppm
	Limit: NMT 500 ppm	NMT 500 ppm
Conclusion	Conform with USP32

Packaging	1kg-15kg packing	2 PE bag inside + 1 foil bag outside in carton
	25kg-50kg packing	2 PE bag inside + 1 foil bag outside in drum
	Other packing	Customized packing
Drum Size	D38cm*H60cm or customized, 25 kg/ drum
Shipping	1-50kg	International Express	Fast and convenient	Door to Door
	50-500kg	Air Transportation	Fast and cheap	To Air Port
	Above 500kg	Sea Transportation	Cheap and convenient	To Port

 

 

 

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