- Product Details
Keywords
- Tranexamic Acid
- Tranexamic Acid TXA
- 4-(Aminomethyl)cyclohexanecarboxylicacid
Quick Details
- ProName: Tranexamic acid
- CasNo: 701-54-2
- Molecular Formula: C8H15NO2
- Appearance: White to off-white crystalline powder
- Application: food use
- DeliveryTime: Within 3 working days
- PackAge: As per buyer's requirement
- Port: Qingdao/ Shanghai/ Tianjin/ Ningbo Por...
- ProductionCapacity: 3000 Metric Ton/Month
- Purity: 99%
- Storage: Cool Dry Place
- Transportation: By express, air, sea, train or road de...
- LimitNum: 1 Kilogram
Superiority
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Details
CAS 701-54-2 Tranexamic Acid TXA Medicine Grade Reduce Excessive Bleeding
Product Description
Tranexamic Acid - Description
Tranexamic acid (TXA) is a synthetic derivative of the amino acid lysine with the chemical formula C8H15NO2. It functions as an antifibrinolytic agent by inhibiting the activation of plasminogen to plasmin, the enzyme responsible for the breakdown of fibrin clots. TXA is widely used in medicine to prevent or reduce excessive bleeding during surgeries, trauma, or medical conditions such as heavy menstrual bleeding. Additionally, it is used in dermatology for its skin-brightening and anti-pigmentation properties.
Technical Data Sheet
Parameter | Value | Description |
---|---|---|
Chemical Name | Tranexamic Acid | Full name |
IUPAC Name | trans-4-(Aminomethyl)cyclohexanecarboxylic acid | Systematic name |
CAS Number | 1197-18-8 | Unique identifier |
Chemical Formula | C8H15NO2 | Molecular structure |
Molecular Weight | 157.21 g/mol | Molecular mass |
Appearance | White to off-white crystalline powder | Visual description |
Solubility | Soluble in water, slightly soluble in ethanol | Solubility properties |
Melting Point | ~300°C (decomposes) | High thermal stability |
pH (1% solution) | 7.0–8.0 | Neutral to slightly basic |
Purity | ≥99% | Pharmaceutical-grade purity |
LogP (Partition Coefficient) | -1.4 | Indicates high water solubility |
Stability | Stable under normal storage conditions | Long shelf life |
Mechanism of Action
Tranexamic acid works by inhibiting plasminogen activation and plasmin activity, preventing the breakdown of fibrin clots. This antifibrinolytic action stabilizes blood clots, reducing bleeding in various medical conditions.
Features
-
Antifibrinolytic Activity:
- Potent inhibitor of fibrinolysis, effective in reducing excessive bleeding.
-
Skin-Brightening Properties:
- Inhibits melanin synthesis by blocking the interaction of melanocytes and keratinocytes, reducing hyperpigmentation.
-
High Water Solubility:
- Easily dissolves in aqueous formulations for medical and dermatological use.
-
Safe and Well-Tolerated:
- Low side effect profile when used at therapeutic doses.
-
Versatile Applications:
- Effective in systemic, local, and topical formulations (e.g., oral tablets, injectables, and creams).
Applications
1. Medical Applications
- Hemostasis:
- Prevents or reduces excessive bleeding in:
- Trauma patients.
- Surgeries (e.g., cardiac, orthopedic, dental).
- Postpartum hemorrhage.
- Menorrhagia (heavy menstrual bleeding).
- Prevents or reduces excessive bleeding in:
- Hereditary Angioedema:
- Reduces the frequency and severity of attacks.
2. Dermatological Applications
- Hyperpigmentation Treatment:
- Used in creams, serums, and oral medications to treat:
- Melasma.
- Post-inflammatory hyperpigmentation (PIH).
- Dark spots and uneven skin tone.
- Used in creams, serums, and oral medications to treat:
- Anti-Aging:
- Helps brighten and even out skin tone.
3. Pharmaceutical Formulations
- Oral Tablets:
- Typically for systemic antifibrinolytic therapy.
- Injectable Solutions:
- Used in emergency and surgical settings.
- Topical Creams and Serums:
- For cosmetic and dermatological purposes.
Packaging | 1kg-15kg packing | 2 PE bag inside + 1 foil bag outside in carton | ||
25kg-50kg packing | 2 PE bag inside + 1 foil bag outside in drum | |||
Other packing | Customized packing | |||
Drum Size | D38cm*H60cm or customized, 25 kg/ drum | |||
Shipping | 1-50kg | International Express | Fast and convenient | Door to Door |
50-500kg | Air Transportation | Fast and cheap | To Air Port | |
Above 500kg | Sea Transportation | Cheap and convenient | To Port |
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